Crystalline Solid Pharmaceutical Raw Materials Meg

Quick Details:   Product Name:Megestrol acetate CAS:595-33-5 MF:C24H32O4 MW:384.51 EINECS: 209-864-5 mp :214C refractive index :11 (C=2, CHCl3) storage temp. :Refrigerator Chemical Properties:Crystalline Solid Usage:Progestogen;Progesterone receptor agonist   Description:   Megestrol acetate (MGA) (INN, USAN, BAN, JAN) (brand names Megace, Megace ES), also known as 17-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin of the 17-hydroxyprogesterone group that is used in the treatment of breast and endometrial cancer and as an appetite stimulant.[5][6][7] It is the 17-acetate ester of megestrol, which, in contrast to MGA, was never marketed for clinical use.[5][6] The term megestrol is often inappropriately used as a synonym for MGA, and when it is used, it almost always refers to MGA rather actually than megestrol.   Medical uses:   MGA is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers.When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induce weight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.   In addition to its use in humans, MGA has been used extensively in veterinary medicine in the treatment of medical conditions in cats and dogs   Side effects:   The most common side effect of MGA is weight gain. Other side effects may include nausea, vomiting, nightmares, impotence, edema, breakthrough bleeding, and shortness of breath. Rare and more severe side effects may include thrombophlebitis and pulmonary embolism.It may also cause glucocorticoid-related adverse effects such as adrenal insufficiency in some individuals and/or cases (especia

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