Cyclophilin A from Human, Recombinant
ID:551588 View:3066次 | Collection |
Date Listed: | 2018-03-20 15:22:27 | Country: | United States»New York»Shirley |
Poster: | Lisa Clara | Company: | Creative Enzymes |
Location: | 45-1 Ramsey Road, Shirley, NY 11967, USA | Website: | Creative Enzymes |
Email: | contact@creative-enzymes.com | Mobile: | 16316197922 |
Fax: | 6319388127 | MSN: |
Cyclophilins are peptidyl prolyl isomerases that catalyze the cis-trans isomerization of X-Pro peptide bonds. They are highly-conserved cytoplasmic enzymes that accelerate protein folding and facilitate HIV infectivity. Cyclosporin A binds to cyclophilin and inhibits its activity. The cyclosporin A-cyclophilin complex binds to calcineurin and inhibits T-cell activation. The structure of human, recombinant cyclophilin is given by Holzman, et al.
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