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Hot-sell Product MK-677

ID:516950 View:3122 Collection
Date Listed: 2018-07-25 10:30:21 Country: China»Hubei»Wuhan
Poster: Sara Company: Wuhan Saith Chemical Co., Ltd
Location: No.9 Nanhu Road, Hongshan District Website: Wuhan Saith Chemical Co., Ltd
Email: sara@saith.com.cn Mobile:
Fax: MSN:

Product Name:MK-677 CAS NO:*-10-0 Molecular Formula: C27H36N4O5S.CH4O3S Molecular weight: 624.776 Appearance:Powder Detail: MK-677 also known as Ibutamoren, MK-0677, L-163,191 is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. MK677 has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat. It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.

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