Pharmaceutical Raw Materials Desonide CAS 638-94-8

Desonide Ointment, 0.05% contains Desonide (Pregna - 1,4 - diene - 3,20 - dione,11,21 - dihydroxy - 16,17 - [(1 - methylethylidene)bis(oxy)] - ,(11β,16α)) a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primary synthetic steroids used topically as anti-inflammatory and antipruritic agents. Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula: The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L. Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.

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