SR9011/steroid*r.com

CAS *-29-9 SR9011 Product Name:SR9011 CAS NO.:*-29-9 Molecular Formula:C23H31ClN4O3S Molecular Weight:479.* Purity:99% Appearance:White Powder Grade:Pharmaceutical Grade SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.

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