Estriol Estrogen Steroid Estriol (oestriol, E3)

Estriol Estrogen Steroid Estriol (oestriol, E3) USP CAS 50-27-1 Synonyms: oestriol; 1,3,5(10)-Estratriene-3,16a,17b-triol CAS: 50-27-1 EINECS: 200-022-2 Assay: 97.0%-102.0%, USP30. Packing: foil bag or tin. Delivery: Express courier. Character: White crystalline powder. Standards:USP27 Usage: A metabolite of Estradiol. An estrogenic metabolite considerably less potent than the hormone Estradiol. pharmaceutical material, Steroid hormone, estrogen. Standards:USP27 Estriol (also oestriol or E3) is one of the three main estrogens produced by the human body. Estriol is only produced in significant amounts during pregnancy as it is made by the placenta from 16-hydroxydehydroepiandrosterone sulfate (16-OH DHEAS), an androgen steroid made in the fetal liver and adrenal glands. The human placenta produces pregnenolone and progesterone from circulating cholesterol. Pregnenolone is converted in the fetal adrenal gland into dehydroepiandrosterone (DHEA), a C19 steroid, and then subsequently sulfonated to dehydroepiandrosterone sulfate (DHEAS). DHEAS is converted to 16-OH DHEAS in the fetal liver. The placenta converts 16-OH DHEAS to estriol, and is the predominant site of estriol synthesis.

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