Sibutramine Hydrochloride

Sibutramine Hydrochloride Alias: Reductil CAS No: *-00-7 MF: C17H27Cl2N MW: 316.31     Purity: 99% Appearance: White powder, soluble in methanol.       Applications:   Medicine reducing weight and antidepressants. Sibutramine is well absorbed from the GI tract (77%), but undergoes considerable first-pass metabolism, reducing its bioavailability. The drug itself reaches its peak plasma level after 1 hour and has also a half-life of 1 hour. Sibutramine is metabolized by cytochrome P450 isozyme CYP3A4 into two pharmacologically-active primary and secondary amines (called active metabolites 1 and 2) with half-lives of 14 and 16 hours, respectively. Peak plasma concentrations of active metabolites 1 and 2 are reached after three to four hours. The following metabolic pathway mainly results in two inactive conjugated and hydroxylated metabolites (called metabolites 5 and 6). Metabolites 5 and 6 are mainly excreted in the urine.

Please Note that this information was issued on BestB2B.com!

High Quality TC TG TB Oil Seal NBR FKM ACM VMQ Oil2024-02-03

costa rica liquid nitrogen sample storage tank 2024-02-02

NQKSF Oil Seal Brand New High Quality FKM Seals2024-02-01

Syria nitrogen semen tank KGSQ five-wheeled cart2024-01-31

Honduras large diameter liquid nitrogen container2024-01-29

Wholesale Good Quality NQK O Ring Seals2024-01-29

Charging market environment continues to evolve2024-01-29

EVs High Voltage Cable Development Thread2024-01-29

China supply Support ring FK4E39-K for power plant2024-01-29

Lock nutboiler feedwater pump HPT200-330M for powe2024-01-29

China Manufacturer Respirator DG600-240-05-15-00 f2024-01-29

China made Hu bevel gear 0130/0010/0140 for steam 2024-01-29

Liquid-cooled cables for EV high-power charging2024-01-29

EV High Voltage Cable Connection Differences2024-01-29

Made In China Gearbox Seals Dustproof Oil Seal2024-01-26