bile acid

The newly synthesized and recycled bile acids are secreted into the bile ducts to prevent a high concentration gradient of cholestasis in the liver. The active transport of bile acids is an important factor in regulating the formation and flow of bile acids. The secretion of bile acids also highly affects the secretion of cholesterol, phospholipids, and bilirubin into the bile. The osmotic pressure generated by the active transport of bile acids leads to an increase in the secretion of water and electrolytes into the bile ducts, thereby increasing the amount of bile flow through the bile ducts. Cholic acid synthesis The physiological role of bile acid in the gallbladder Bile acids are stored in the gallbladder and concentrated 5-10 times. After eating, the gallbladder shrinks under the action of trypsin. During contraction, the gallbladder acts like a motor, driving the enterohepatic circulation. Normally, the bile acid concentration in the duodenum rises sharply within 30 minutes after the meal is digested.

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