Human ITGAL blocking peptide
ID:574510 View:782次 | Collection |
Date Listed: | 2018-12-24 14:09:50 | Country: | United States»New York»Shirley |
Poster: | Emily Dean | Company: | Creative-Diagnostics |
Location: | 45-1 Ramsey Road, Shirley, NY 11967, USA | Website: | Creative-Diagnostics |
Email: | contact@creative-diagnostics.com | Mobile: | 6316197922 |
Fax: | MSN: |
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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