Cofilin 2 peptide
ID:574517 View:1263次 | Collection |
Date Listed: | 2018-12-24 14:21:27 | Country: | United States»New York»Shirley |
Poster: | Emily Dean | Company: | Creative-Diagnostics |
Location: | 45-1 Ramsey Road, Shirley, NY 11967, USA | Website: | Creative-Diagnostics |
Email: | contact@creative-diagnostics.com | Mobile: | 6316197922 |
Fax: | MSN: |
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009].
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