RGS14 peptide
ID:575402 View:1340次 | Collection |
Date Listed: | 2019-02-23 15:35:47 | Country: | United States»New York»Shirley |
Poster: | Emily Dean | Company: | Creative-Diagnostics |
Location: | 45-1 Ramsey Road, Shirley, NY 11967, USA | Website: | Creative-Diagnostics |
Email: | contact@creative-diagnostics.com | Mobile: | 6316197922 |
Fax: | MSN: |
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. https://www.creative-diagnostics.com/RGS14-peptide-*-436.htm
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