CAS *-41-8 Povidone Iodine

Product Name:Povidone Iodine Alias：Betadine; Efo-dine；PVP-Iodine CAS Registry Number:*-41-8 Molecular Formula:C6H9I2NO Molecular Weight: 364.9507 Melt Point:300℃ Flash Point:93.9°C Appearance:white powder Boiliing Point:217.6°C at 760 mmHg Vapor Pressure:0.132mmHg at 25°C Povidone-iodine (PVP-I), brand name Wokadine, Pyodine, and Betadine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. While povidone iodine has long been used by surgeons as a preoperative antiseptic, researchers have been looking at the agent for treating viral conjunctivitis as well as other ocular diseases. The microbicidal action spectrum of povidone iodine (PI) is broad, even after short exposure times. Further, unlike local antibiotics and other antiseptic substances, no resistance seems to develop. The high degree of bactericidal efficiency with respect to highly resistant gram-positive pathogenic micro-organisms, such as methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus strains, has made the agent particularly useful and significant for hospital hygiene. Povidone iodine has traditionally been used by surgeons as a preoperative antiseptic. Cheaper than topical antibiotics, it is recognized as a staple solution for preparing the eye for surgery. About 2 years ago, a stir was created when an ophthalmologist published anecdotal evidence that a brief povidone iodine eye wash in patients known to be suffering from viral conjunctivitis successfully helped to resolve the malady far faster than observation and supportive therapy alone. Since that time, investigators have been evaluating the agent to officially validate its use in this regard as well as potentially expand its role in the management of ocular disease. (Shovlin JP, Abel R. Steroids, povidone iodine recommended for adenoviral keratoconjunctivitis.Primary Care Optometry News....

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