Phenacetin

Phenacetin is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887 until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized into paracetamol, which replaced it in some over-the-counter medications following the ban on phenacetin. Applications： Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an “A.P.C.” or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent’s APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR *). It was also banned in India. As a result some branded, previously phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roche’s Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin’s carcinogenicity. Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.Due to low cost phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.

Please Note that this information was issued on BestB2B.com!

Insulation Panel,roof panels2024-01-29

EPS sandwich panel2024-01-29

Insulated Metal Panels Increas2024-01-29

Insulated Metal Roof Panel2024-01-29

Light Insulated Metal Wall Pa2024-01-29

Insulated Metal Wall Panels2024-01-29

Insulated sandwich panels / In2024-01-29

Trapezoidal Roof Panel / Wall2024-01-29

100G QSFP28 SWDM4 100m LC Opti2024-02-01

100G QSFP28 SR4 100M MPO Optic2024-02-01

200G QSFP56 SR4 100m MPO Optic2024-02-01

400G OSFP SR8 100m MPO Optical2024-02-01

400G QSFP-DD LR8 10KM LC Optic2024-02-01

400G QSFP-DD LR4 10KM LC Media2024-02-01

400G QSFP-DD 4x100G LR 10KM 2024-01-29