Trimethoprim

Trimethoprim is a chemical substance with the formula: C14H18N4O3.C3H6O3. Chinese name Trimethoprim Foreign name Trimethoprim lactate Molecular formula :C14H18N4O3.C3H6O3 Molecular mass: 380.40 Structural formula Chinese name: trimethoprim-lactic acid; lactate TMP; trimethoprim-lactam Uses: Antibacterial drugs. PH: 4.6-6.0 【Appearance】: white or almost white cake 【Properties】 This product is white or almost white crystalline powder; odorless, bitter taste. 【Pharmacological effects】 1. The combination of this product with sulfa drugs can cause double blockage of the bacteria's folic acid metabolism, and increase its effect several times to dozens of times. It exhibits bactericidal action and can also reduce the production of resistant strains. 2, the interaction of drugs; TMP can enhance the antibacterial effects of tetracycline, penicillin, erythromycin, gentamicin, etc., combined with berberine, berberine significantly enhanced antibacterial activity, as a broad-spectrum non-selective antibacterial drugs. [Adaptive disease] often used in combination with sulfonamides at ratios of 1:4 to 5 for respiratory, digestive, and genitourinary infections, sepsis, and cellulitis. It can also be used in combination with other antibacterial drugs to achieve synergy.

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